Evaluation of antioxidants in cadmium toxicity in poultry.
Swapna G., Reddy A. G., Haritha C.
Author Affiliation: Department of Pharmacology and Toxicology, College of Veterinary Science, Rajendra Nagar, Hyderabad, India.
Indian Veterinary Journal 87 : 1041-1042
Abstract : Eighty day-old broiler chicks were divided into 8 groups which were fed a basal diet only (Group I), diet + 100 ppm cadmiun (Group II), cadmium + Emblica officinalis [Phylannthus emblica] (Group III), cadmium + vitamin E (Group IV) and cadmium + Stressroak (containing Withania somnifera, Emblica officinalis, Ocimum sanctum, [Ocimum tenuiflorum] Mangifera indica and shilajit, Group V) for 6 weeks, while Groups VI, VII and VIII were fed diets with cadmium for 4 weeks and Emblica officinalis, vitamin E and Stressroak, respectively, for 2 weeks. Blood samples were analysed on the 4th and 6th weeks for lipid profiles and haemagglutination inhibition. It was shown that total cholesterol, triglycerides and low density lipoprotein cholesterol significantly increased, while high density lipoprotein significantly decreased in Groups II, VI, VII and VIII. Total cholesterol significantly increased in Groups III, IV and V at the end of the 4th week and then decreased at the end of the 6th week. Lipid profiles returned to normal in Groups VI, VII and VIII after treatment. Haemagglutination inhibition significantly decreased in Groups II, III, IV and V and significantly increased in Groups VI, VII and VIII. These results show the beneficial effects of antioxidants and immunostimulants in negating the adverse effects of cadmium toxicity in broilers.