Therapeutic evaluation of herbal formulations against canine demodicosis.
Roy S., Roy M.
Author Affiliation: Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Anjora, Durg, 491 001, Chhattisgarh, India.
Indian Veterinary Journal 85 : 672-673
Abstract : Twenty-six dogs of different breeds and age, suffering from localized (n=16) and generalized (n=10) demodecosis, were grouped into three. Group A (5 generalized and 5 localized) were treated topically twice a day for one week and once daily thereafter until complete recovery with Zerokeet which contains Cedrus deodara, Pogamia glabra, Eucalyptus globulus and Acorus calamus. Group B (5 generalized and 5 localized) were treated with Zerokeet and Newcharm gel which contains C. deodara, P. glabra, Azadirachta indica, E. globulus and A. calamus. Newcharm gel was applied topically twice daily for 7 days and once daily for 5 days, followed by alternate day and Charmid capsule (Curcuma longa, Allium sativum, C. deodara, Berberis aristata, A. indica, Mangifera indica, Shilajit extract and Saussurea lappa extract). Group C (6 localized) served as infected control. The efficacy of treatment was assessed based on healing of skin lesions, hair regrowth and the results of skin scrapings. Improvement in the lesions was observed in dogs of Groups A and B on the 21st day of treatment. However, greater improvement was observed in Group B compared to Group A. After 3 months post-treatment, recurrence was observed in two dogs of Group A, while no recurrence was observed in dogs of Group B. The study showed that although Zerokeet is effective against canine demodecosis, the combination of Zerokeet, Newcharm and Charmid showed better efficacy.