Patents on Mango

Patent Information : 101003558
Title : Glycoside class compound of mango, preparation method, and application in area of medicine
Author : No.2 Army Medical College, P.L.A
Field belongs to : Medicine
Abstract : This invention discloses compounds with natural product mangiferin as the frame. The general chemical structure of the compounds is shown in formula I, wherein, R1 and R2 are C1-20 linear or branched alkyl, benzyl, or substituted benzyl. The substituent is halogen, alkyl, etc. The compounds have strong inhibitive activity on protein tyrosine phosphatase 1B (PTP1B). This invention also discloses a method for preparing the compounds. The compounds can be used to treat diseases related to PTP1B inhibition, including diabetes type 2.
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